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Meh, for me VM DNS gave me a server in the Netherlands and Google DNS gave me one in Switzerland. Unlike yours which looks like west coast US - course it's going to be slow.

C:\Users\Administrator>nslookup iso.esd.microsoft.com 194.168.4.100
Server: cache1.service.virginmedia.net
Address: 194.168.4.100

Non-authoritative answer:
Name: a2047.d.akamai.net
Addresses: 88.221.216.26
88.221.216.19
88.221.216.17
88.221.216.16
88.221.216.33
88.221.216.18
88.221.216.35
88.221.216.8
88.221.216.11
Aliases: iso.esd.microsoft.com
iso.esd.microsoft.com.nsatc.net
main.esd.microsoft.com.nsatc.net
esd.microsoft.com.edgesuite.net


C:\Users\Administrator>nslookup iso.esd.microsoft.com 8.8.8.8
Server: google-public-dns-a.google.com
Address: 8.8.8.8

Non-authoritative answer:
Name: a2047.d.akamai.net
Addresses: 77.109.171.155
77.109.171.192
77.109.171.169
77.109.171.129
77.109.171.139
77.109.171.154
77.109.171.176
77.109.171.186
77.109.171.161
Aliases: iso.esd.microsoft.com
iso.esd.microsoft.com.nsatc.net
main.esd.microsoft.com.nsatc.net
esd.microsoft.com.edgesuite.net

C:\Users\Administrator>tracert 88.221.216.26

Tracing route to a88-221-216-26.deploy.akamaitechnologies.com [88.221.216.26]
over a maximum of 30 hops:

1 <1 ms <1 ms <1 ms d.lan [10.1.0.11]
2 29 ms 26 ms 28 ms cpc5-sgyl34-2-0-gw.sgyl.cable.virginmedia.com [92.235.188.1]
3 30 ms 29 ms 24 ms sgyl-core-1a-ge133.network.virginmedia.net [81.97.48.37]
4 16 ms 18 ms 21 ms sgyl-core-1b-v15.network.virginmedia.net [80.195.0.6]
5 7 ms 7 ms 11 ms sgyl-core-2b-ae2-0.network.virginmedia.net [195.182.178.94]
6 16 ms 11 ms 18 ms leed-bb-1b-ae5-0.network.virginmedia.net [81.97.48.81]
7 21 ms 22 ms 23 ms 62.252.224.238
8 69 ms 31 ms 27 ms xe-5-2-0-xcr1.lnd.cw.net [195.2.10.241]
9 34 ms 44 ms 28 ms xe-11-0-0-xcr1.lsw.cw.net [195.2.25.29]
10 50 ms 83 ms 79 ms xe-11-1-0-xcr1.amd.cw.net [195.2.25.102]
11 48 ms 48 ms 40 ms xe-5-0-0-xcr1.amt.cw.net [195.2.28.78]
12 37 ms 36 ms 43 ms akamai.telecity4.nl-ix.net [193.239.116.226]
13 36 ms 45 ms 53 ms a88-221-216-26.deploy.akamaitechnologies.com [88.221.216.26]

Trace complete.

C:\Users\Administrator>tracert 77.109.171.155

Tracing route to a77.109.171-155.deploy.akamaitechnologies.com [77.109.171.155]
over a maximum of 30 hops:

1 <1 ms <1 ms <1 ms d.lan [10.1.0.11]
2 26 ms 11 ms 13 ms cpc5-sgyl34-2-0-gw.sgyl.cable.virginmedia.com [92.235.188.1]
3 47 ms 8 ms 16 ms sgyl-core-1a-ge225.network.virginmedia.net [81.97.49.149]
4 33 ms 12 ms 8 ms sgyl-core-2a-ae2-0.network.virginmedia.net [195.182.178.90]
5 17 ms 16 ms 15 ms manc-bb-1c-ae6-0.network.virginmedia.net [81.97.48.77]
6 14 ms 11 ms 12 ms manc-bb-1a-ae11-0.network.virginmedia.net [213.105.159.85]
7 36 ms 38 ms 34 ms popl-bb-1b-as3-0.network.virginmedia.net [62.252.192.158]
8 25 ms 21 ms 20 ms tele-ic-5-ae0-0.network.virginmedia.net [213.105.159.117]
9 44 ms 23 ms 35 ms linx-2.init7.net [195.66.226.175]
10 65 ms 53 ms 53 ms r1fra1.core.init7.net [77.109.128.38]
11 50 ms 42 ms 54 ms r1fra3.core.init7.net [77.109.128.222]
12 58 ms 49 ms 42 ms a77.109.171-155.deploy.akamaitechnologies.com [77.109.171.155]

Trace complete.

On second, third, and fourth attempts, VM DNS gave me Netherlands, Netherlands and Netherlands again, while Google DNS gave me Switzerland, USA, Switzerland. Mysteriously no sign of any UK Akamai servers.