[zing]

goto control panel and click classic view.Then click system ,hardware then device manager and see if there are any drivers missing. (yellow triangle) if not close back to control panel and click sounds and audio devices audio and then audio make sure device is present there. If all present there check cables etc and make sure its not been muted

There isnt a Vista driver on the Asus site for that board but im guessing there is a generic driver as part of windows do as I asked above and if no joy perhaps run windows update to see if there is a driver there if not we will investigate further.I got an old soundblaster 5.1 with little value which would just plug in and work I imagine

(please note directions have been pulled from my head as im in bed on my xp laptop but there will be nearly right but expect some slight differences to what ive said)