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Thalidomide effect mystery solved
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Old 12-03-2010, 09:02   #1
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Thalidomide effect mystery solved

http://news.bbc.co.uk/1/hi/sci/tech/8562998.stm

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Scientists have discovered the primary mechanism by which thalidomide causes malformed limbs in developing embryos.
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This finding could help the development of safer thalidomide-like drugs.
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Thalidomide can be effective in the treatment of certain cancers and leprosy, but its infamous side-effect, which is known as teratogenicity, mean that for women its use remains risky and controversial.
I hope that this will help to make sure no more such cases occur but I also hope that when they produce the newer drugs the pharmaceutical companies might be rather more generous in their financial dealing with their 'victims' seeing how they were unwitting guinea pigs.
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Old 12-03-2010, 09:42   #2
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Re: Thalidomide effect mystery solved

Good to know the whys and wherefores, just a shame it took 50 years.

Based on the conclusion (in this laypersons view) it could well be the cellular effect it has on embryonic development is exactly why it works for treating cancer.
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Old 12-03-2010, 14:55   #3
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Re: Thalidomide effect mystery solved

my Mother was offered this when she was pregnant with me thank Christ she didnt accept it
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Old 12-03-2010, 15:15   #4
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Re: Thalidomide effect mystery solved

Quote:
Originally Posted by zing View Post
my Mother was offered this when she was pregnant with me thank Christ she didnt accept it
Are you telling porkies about your age zing?


Was only available from 1957 to 1961 My mother actually had the prescription when I was on the way, just didn't get it filled out.
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Old 12-03-2010, 16:21   #5
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Re: Thalidomide effect mystery solved

in which case my old dear lied to me then. Does not surprise me as she is one for trying to big herself up and make her look like she did something good. ( as you can tell I am a tad bitter )
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Old 12-03-2010, 18:02   #6
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Re: Thalidomide effect mystery solved

Would rather be 10 years younger than having been under threat.
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Old 12-03-2010, 18:15   #7
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Re: Thalidomide effect mystery solved

would rather not have a mother that lies to me lol
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